Covalently immobilized biosignal molecule materials for tissue engineering

Yoshihiro Ito

doi:10.1039/B708359A

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Soft Matter

Issue 1, 2008

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Covalently immobilized biosignal molecule materials for tissue engineering

Yoshihiro Ito

Soft Matter, 2008, 4, 46-56

DOI: 10.1039/B708359A
Received 01 Jun 2007, Accepted 05 Sep 2007
First published on the web 08 Oct 2007

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Immobilization of biosignal molecules including growth factors and cytokines is important for developing biologically active materials which can contribute to tissue engineering as a component. The immobilization has more meanings than only immobilization of the enzyme in a bioreactor or ligand–receptor interactions, because the immobilized biosignal molecules work on cells which have very complex structures and functions. This review discusses recent progress in immobilization of biosignal molecules, including the mechanisms and design concepts.

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Soft Matter

Covalently immobilized biosignal molecule materials for tissue engineering

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