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Issue 21, 2008
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Pseudouridines in rRNA helix 69 play a role in loop stacking interactions

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Abstract

The 1H NMR spectra of RNAs representing E. coli23S rRNA helix 69 with [1,3-15N]pseudouridine modification at specific sites reveal unique roles for pseudouridine in stabilizing base-stacking interactions in the hairpin loop region.

Graphical abstract: Pseudouridines in rRNA helix 69 play a role in loop stacking interactions

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Publication details

The article was received on 24 Jul 2008, accepted on 01 Sep 2008 and first published on 19 Sep 2008


Article type: Communication
DOI: 10.1039/B812731J
Citation: Org. Biomol. Chem., 2008,6, 3892-3895
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    Pseudouridines in rRNA helix 69 play a role in loop stacking interactions

    J. Desaulniers, Y. Chang, R. Aduri, S. C. Abeysirigunawardena, J. SantaLucia, Jr. and C. S. Chow, Org. Biomol. Chem., 2008, 6, 3892
    DOI: 10.1039/B812731J

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