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Issue 21, 2008
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Enhancement of entrapping ability of dendrimers by a cubic silsesquioxane core

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Abstract

We report that a polyhedral oligomeric silsesquioxane (POSS) core can enhance the entrapping ability of dendrimers. Compared to the G2 PAMAM dendrimer, the G2 POSS-core dendrimer can entrap a larger amount of guest molecules without loss of affinity, and consequently, the water solubility of the entrapped guest molecules can be increased. In addition, we demonstrated that a fluorophore entrapped in the G2 POSS-core dendrimer was prevented from undergoing fluorescence photobleaching.

Graphical abstract: Enhancement of entrapping ability of dendrimers by a cubic silsesquioxane core

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Publication details

The article was received on 18 Jul 2008, accepted on 22 Sep 2008 and first published on 29 Sep 2008


Article type: Communication
DOI: 10.1039/B812349G
Citation: Org. Biomol. Chem., 2008,6, 3899-3901
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    Enhancement of entrapping ability of dendrimers by a cubic silsesquioxane core

    K. Tanaka, K. Inafuku, K. Naka and Y. Chujo, Org. Biomol. Chem., 2008, 6, 3899
    DOI: 10.1039/B812349G

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