Jump to main content
Jump to site search

Issue 18, 2008
Previous Article Next Article

Synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I

Author affiliations

Abstract

The synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid is reported along with the X-ray crystal structure of its complex with human arginase I, revealing unique coordination interactions with two manganese ions in the enzyme active site.

Graphical abstract: Synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 10 Jul 2008, accepted on 15 Jul 2008 and first published on 06 Aug 2008


Article type: Communication
DOI: 10.1039/B811797G
Citation: Org. Biomol. Chem., 2008,6, 3240-3243
  •   Request permissions

    Synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I

    T. Y. Zakharian, L. Di Costanzo and D. W. Christianson, Org. Biomol. Chem., 2008, 6, 3240
    DOI: 10.1039/B811797G

Search articles by author