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Issue 17, 2008
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Generation of molecular diversity using a complexity-generating MCR-platform towards triazinane diones

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Abstract

Triazinane diones, readily generated by a recently reported multicomponent reaction, can be easily alkylated with various alkyl halides, allowing a wide variety of complexity-generating secondary reactions. Because of the high variability of the initial multicomponent reactions and the multiple possibilities for participation of substituents in the secondary reactions, a highly diverse set of complex products was obtained in short and efficient reaction sequences.

Graphical abstract: Generation of molecular diversity using a complexity-generating MCR-platform towards triazinane diones

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Publication details

The article was received on 28 Apr 2008, accepted on 05 Jun 2008 and first published on 03 Jul 2008


Article type: Paper
DOI: 10.1039/B807138A
Citation: Org. Biomol. Chem., 2008,6, 3158-3165
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    Generation of molecular diversity using a complexity-generating MCR-platform towards triazinane diones

    B. Groenendaal, E. Ruijter, F. J. J. de Kanter, M. Lutz, A. L. Spek and R. V. A. Orru, Org. Biomol. Chem., 2008, 6, 3158
    DOI: 10.1039/B807138A

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