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Issue 14, 2008
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Concise synthesis of the tricyclic core of lycoposerramine S

Mark C. Elliott,*a  Nahed N. E. El Sayeda  and  James S. Painea 
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* Corresponding authors

a School of Chemistry, Cardiff University, Main College Building, Park Place, Cardiff, UK
E-mail: elliottmc@cardiff.ac.uk
Fax: +44 (0)29 20874030
Tel: +44 (0)29 20874686

Abstract

The tricyclic core of lycoposerramine S has been synthesised in 10 steps from a symmetrical cyclohexadiene precursor by way of a desymmetrising free-radical cyclisation and iodocyclisation.

Graphical abstract: Concise synthesis of the tricyclic core of lycoposerramine S

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Publication details

The article was received on 18 Mar 2008, accepted on 14 Apr 2008 and first published on 16 May 2008


Article type: Paper
DOI: 10.1039/B804664F
Citation: Org. Biomol. Chem., 2008,6, 2611-2618
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    Concise synthesis of the tricyclic core of lycoposerramine S

    M. C. Elliott, N. N. E. El Sayed and J. S. Paine, Org. Biomol. Chem., 2008, 6, 2611
    DOI: 10.1039/B804664F

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