Jump to main content
Jump to site search

Issue 8, 2008
Previous Article Next Article

Recent advances in enantioselective [2 + 2 + 2] cycloaddition

Author affiliations

Abstract

Enantioselective cycloaddition using chiral transition metal catalysts is an atom-economical and efficient synthetic tool for the construction of chiral carbo- and heterocyclic skeletons. This short account discloses our recent results of inter- and intramolecular enantioselective [2 + 2 + 2] cycloadditions of alkyne and/or alkene moiety(ies). Chiral iridium complexes catalyzed the alkyne trimerization for the generation of axial chirality(ies), and chiral rhodium ones catalyzed alkynealkynealkene cyclization for the generation of a quaternary carbon including spirocyclic system.

Graphical abstract: Recent advances in enantioselective [2 + 2 + 2] cycloaddition

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 03 Jan 2008, accepted on 15 Feb 2008 and first published on 12 Mar 2008


Article type: Emerging Area
DOI: 10.1039/B720031E
Citation: Org. Biomol. Chem., 2008,6, 1317-1323
  •   Request permissions

    Recent advances in enantioselective [2 + 2 + 2] cycloaddition

    T. Shibata and K. Tsuchikama, Org. Biomol. Chem., 2008, 6, 1317
    DOI: 10.1039/B720031E

Search articles by author