Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products
Jonathan
Kennedy
Nat. Prod. Rep., 2008, 25, 25-34
DOI:
10.1039/B707678A
Received
17 Jul 2007,
First published on the web
04 Sep 2007
A review, with 52 references, describing recent advances utilising mutasynthesis and metabolic engineering for the generation of new, or difficult to source, metabolites.
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