Effective delivery of IgG-antibodies into infected cells via dendritic molecular transporter conjugate IgGMT

Sharon K. Hamilton; Mine R. Ikizler; Christian Wallen; Peter F. Wright; Eva Harth

doi:10.1039/B816645E

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Molecular BioSystems

Issue 12, 2008

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Effective delivery of IgG-antibodies into infected cells via dendritic molecular transporter conjugate IgGMT

Sharon K. Hamilton , Mine R. Ikizler , Christian Wallen , Peter F. Wright and Eva Harth

Mol. BioSyst., 2008, 4, 1209-1211

DOI: 10.1039/B816645E
Received 25 Sep 2008, Accepted 16 Oct 2008
First published on the web 27 Oct 2008

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IgG antibody–transporter conjugates enable intracellular uptake of biologically active IgG antibodies that inhibit viral mediated syncytia formation in respiratory syncytial virus green fluorescent protein (RSV-GFP) infected human epithelial cells (HEp-2).

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Sharon K. Hamilton
Mine R. Ikizler
Christian Wallen
Peter F. Wright
Eva Harth

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Molecular BioSystems

Effective delivery of IgG-antibodies into infected cells via dendritic molecular transporter conjugate IgGMT

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