Chemical site-selective prenylation of proteins

David P. Gamblin; Sander van Kasteren; Gonçalo J. L. Bernardes; Justin M. Chalker; Neil J. Oldham; Antony J. Fairbanks; Benjamin G. Davis

doi:10.1039/B802199F

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Molecular BioSystems

Issue 6, 2008

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Chemical site-selective prenylation of proteins

David P. Gamblin , Sander van Kasteren , Gonçalo J. L. Bernardes , Justin M. Chalker , Neil J. Oldham , Antony J. Fairbanks and Benjamin G. Davis

Mol. BioSyst., 2008, 4, 558-561

DOI: 10.1039/B802199F
Received 07 Feb 2008, Accepted 25 Apr 2008
First published on the web 02 May 2008

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Abstract
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Compounds
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A direct thionation procedure allows conversion of allylic alcohols into the corresponding thiols, the products of which are immediately compatible with one-pot site-selective selenenyl sulfide mediated protein conjugation.

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Articles By

David P. Gamblin
Sander van Kasteren
Gonçalo J. L. Bernardes
Justin M. Chalker
Neil J. Oldham
Antony J. Fairbanks
Benjamin G. Davis

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Molecular BioSystems

Chemical site-selective prenylation of proteins

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