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Issue 6, 2008
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Chemical site-selective prenylation of proteins

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Abstract

A direct thionation procedure allows conversion of allylic alcohols into the corresponding thiols, the products of which are immediately compatible with one-pot site-selective selenenyl sulfide mediated protein conjugation.

Graphical abstract: Chemical site-selective prenylation of proteins

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Publication details

The article was received on 07 Feb 2008, accepted on 25 Apr 2008 and first published on 02 May 2008


Article type: Paper
DOI: 10.1039/B802199F
Citation: Mol. BioSyst., 2008,4, 558-561
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    Chemical site-selective prenylation of proteins

    D. P. Gamblin, S. van Kasteren, G. J. L. Bernardes, J. M. Chalker, N. J. Oldham, A. J. Fairbanks and B. G. Davis, Mol. BioSyst., 2008, 4, 558
    DOI: 10.1039/B802199F

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