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Issue 4, 2008
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Gene regulation technologies in zebrafish

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Achieving the potential of zebrafish models in biomedical research is contingent on the development of reverse-genetic resources. This review describes current technologies for genetic perturbations in zebrafish, including an ecdysone receptor-based system that permits conditional transgene expression. Such methodologies promise to enable new zebrafish models for interrogating human physiology and disease.

Graphical abstract: Gene regulation technologies in zebrafish

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The article was first published on 20 Feb 2008

Article type: Highlight
DOI: 10.1039/B718447F
Citation: Mol. BioSyst., 2008,4, 300-308
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    Gene regulation technologies in zebrafish

    H. Esengil and J. K. Chen, Mol. BioSyst., 2008, 4, 300
    DOI: 10.1039/B718447F

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