Issue 2, 2008

Informatics and computational strategies for the study of lipids

Abstract

Recent advances in mass spectrometry (MS)-based techniques for lipidomic analysis have empowered us with the tools that afford studies of lipidomes at the systems level. However, these techniques pose a number of challenges for lipidomic raw data processing, lipid informatics, and the interpretation of lipidomic data in the context of lipid function and structure. Integration of lipidomic data with other systemic levels, such as genomic or proteomic, in the context of molecular pathways and biophysical processes provides a basis for the understanding of lipid function at the systems level. The present report, based on the limited literature, is an update on a young but rapidly emerging field of lipid informatics and related pathway reconstruction strategies.

Graphical abstract: Informatics and computational strategies for the study of lipids

Article information

Article type
Highlight
Submitted
12 Oct 2007
Accepted
29 Nov 2007
First published
18 Dec 2007

Mol. BioSyst., 2008,4, 121-127

Informatics and computational strategies for the study of lipids

L. Yetukuri, K. Ekroos, A. Vidal-Puig and M. Orešič, Mol. BioSyst., 2008, 4, 121 DOI: 10.1039/B715468B

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