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Issue 2, 2008
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Informatics and computational strategies for the study of lipids

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Abstract

Recent advances in mass spectrometry (MS)-based techniques for lipidomic analysis have empowered us with the tools that afford studies of lipidomes at the systems level. However, these techniques pose a number of challenges for lipidomic raw data processing, lipid informatics, and the interpretation of lipidomic data in the context of lipid function and structure. Integration of lipidomic data with other systemic levels, such as genomic or proteomic, in the context of molecular pathways and biophysical processes provides a basis for the understanding of lipid function at the systems level. The present report, based on the limited literature, is an update on a young but rapidly emerging field of lipid informatics and related pathway reconstruction strategies.

Graphical abstract: Informatics and computational strategies for the study of lipids

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Publication details

The article was received on 12 Oct 2007, accepted on 29 Nov 2007 and first published on 18 Dec 2007


Article type: Highlight
DOI: 10.1039/B715468B
Citation: Mol. BioSyst., 2008,4, 121-127
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    Informatics and computational strategies for the study of lipids

    L. Yetukuri, K. Ekroos, A. Vidal-Puig and M. Orešič, Mol. BioSyst., 2008, 4, 121
    DOI: 10.1039/B715468B

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