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Issue 12, 2008
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A portable surface-enhanced Raman scattering sensor integrated with a lab-on-a-chip for field analysis

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Abstract

An integrated real-time sensing system that uses a portable Raman spectrometer and a micropillar array chip has been developed for field analysis. The problem of poor detection sensitivity, caused by miniaturization in the portable Raman spectrometer, was overcome by using the surface-enhanced Raman scattering (SERS) technique. The problem of poor reproducibility in the SERS detection, caused by different particle sizes and inhomogeneous degrees of aggregation, was also overcome by using continuous flow and homogeneous mixing between the analytes and nanocolloidal silver in a micropillar array microfluidic chip. Two hazardous materials, dipicolinic acid and malachite green, were quantitatively analysed using our integrated portable Raman sensor system. The observed limit of detection was estimated to be 200 ppb and 500 ppb, respectively. Our proposed analytical method, using a micropillar array PDMS chip and a portable SERS system, offers a rapid and reproducible trace detection capability for hazardous materials in the field.

Graphical abstract: A portable surface-enhanced Raman scattering sensor integrated with a lab-on-a-chip for field analysis

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Publication details

The article was received on 27 May 2008, accepted on 01 Sep 2008 and first published on 20 Oct 2008


Article type: Paper
DOI: 10.1039/B808835G
Citation: Lab Chip, 2008,8, 2214-2219
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    A portable surface-enhanced Raman scattering sensor integrated with a lab-on-a-chip for field analysis

    L. X. Quang, C. Lim, G. H. Seong, J. Choo, K. J. Do and S. Yoo, Lab Chip, 2008, 8, 2214
    DOI: 10.1039/B808835G

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