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Issue 10, 2008
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An active bubble trap and debubbler for microfluidic systems

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Abstract

We present a novel, fully integrated microfluidic bubble trap and debubbler. The 2-layer structure, based on a PDMS valve design, utilizes a featured membrane to stop bubble progression through the device. A pneumatic chamber directly above the trap is evacuated, and the bubble is pulled out through the gas-permeable PDMS membrane. Normal device operation, including continuous flow at atmospheric pressure, is maintained during the entire trapping and debubbling process. We present a range of trap sizes, from 2 to 10 mm diameter, and can trap and remove bubbles up to 25 μL in under 3 h.

Graphical abstract: An active bubble trap and debubbler for microfluidic systems

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Publication details

The article was received on 29 Apr 2008, accepted on 16 Jul 2008 and first published on 28 Aug 2008


Article type: Technical Note
DOI: 10.1039/B807037G
Citation: Lab Chip, 2008,8, 1733-1737
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    An active bubble trap and debubbler for microfluidic systems

    A. M. Skelley and J. Voldman, Lab Chip, 2008, 8, 1733
    DOI: 10.1039/B807037G

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