Glass coating for PDMS microfluidic channels by sol–gel methods

Adam R. Abate; Daeyeon Lee; Thao Do; Christian Holtze; David A. Weitz

doi:10.1039/B800001H

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Lab on a Chip

Issue 4, 2008

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Glass coating for PDMS microfluidic channels by sol–gel methods

Adam R. Abate , Daeyeon Lee , Thao Do , Christian Holtze and David A. Weitz

Lab Chip, 2008, 8, 516-518

DOI: 10.1039/B800001H
Received 03 Jan 2008, Accepted 12 Feb 2008
First published on the web 20 Feb 2008

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Soft lithography using polydimethylsiloxane (PDMS) allows one to fabricate complex microfluidic devices easily and at low cost. However, PDMS swells in the presence of many organic solvents significantly degrading the performance of the device. We present a method to coat PDMS channels with a glass-like layer using sol–gel chemistry. This coating greatly increases chemical resistance of the channels; moreover, it can be functionalized with a wide range of chemicals to precisely control interfacial properties. This method combines the ease of fabrication afforded by soft-lithography with the precision control and chemical robustness afforded by glass.

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Articles By

Adam R. Abate
Daeyeon Lee
Thao Do
Christian Holtze
David A. Weitz

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Glass coating for PDMS microfluidic channels by sol–gel methods

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