Jump to main content
Jump to site search

Issue 4, 2008
Previous Article Next Article

Model based design of a microfluidic mixer driven by induced charge electroosmosis

Author affiliations

Abstract

Mixing chemical or biological samples with reagents for chemical analysis is one of the most time consuming operations on microfluidic platforms. This is primarily due to the low rate of diffusive transport in liquid systems. Additionally, much research has focused on detection, rather than sample preparation. In response, we describe a mixer for microfluidic sample preparation based on the electrokinetic phenomenon of induced-charge-electroosmosis (ICEO). ICEO creates microvortices within a fluidic channel by application of alternating current (AC) electric fields. The microvortices are driven by electrostatic forces acting on the ionic charge induced by the field near polarizable materials. By enabling mixing to be turned on or off within a channel of fixed volume, these electronically controlled mixers prevent sample dilution—a common problem with other strategies. A three-dimensional model based on the finite volume method was developed to calculate the electric field, fluid flow, and mass transport in a multi-species liquid. After preliminary experiments, the model was used to rapidly prototype a wide range of designs. A new microfabrication process was developed for devices with vertical sidewalls having conductive metal coatings and embedded electrodes. Mixing experiments were carried out in the devices and the results were compared to the model.

Graphical abstract: Model based design of a microfluidic mixer driven by induced charge electroosmosis

Back to tab navigation

Supplementary files

Publication details

The article was received on 12 Nov 2007, accepted on 05 Feb 2008 and first published on 29 Feb 2008


Article type: Paper
DOI: 10.1039/B717416K
Citation: Lab Chip, 2008,8, 565-572
  •   Request permissions

    Model based design of a microfluidic mixer driven by induced charge electroosmosis

    C. K. Harnett, J. Templeton, K. A. Dunphy-Guzman, Y. M. Senousy and M. P. Kanouff, Lab Chip, 2008, 8, 565
    DOI: 10.1039/B717416K

Search articles by author

Spotlight

Advertisements