We have demonstrated the feasibility of semiconductor Compton cameras for multiple molecular imaging in nuclear medicine. The Compton camera used in this work comprises two double-sided orthogonal-strip germaniumdetectors, and their excellent energy resolution enabled discrimination of the nuclides and accurate determination of the scattering angle for γ rays in wide energy range. Three radioactive tracers of 65ZnCl2, 85SrCl2, and iodinated (131I) methylnorcholestenol were injected to a living mouse and were measured simultaneously. Both two- and three-dimensional images of each tracer were obtained by a fixed-angle imaging with a single Compton camera, which reflected the different in vivo behavior of them.
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Journal of Analytical Atomic Spectrometry
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