Jump to main content
Jump to site search

Volume 139, 2008
Previous Article Next Article

Synthesis of well-defined glycopolymers and some studies of their aqueous solution behaviour

Author affiliations

Abstract

Well-defined polymers with carbohydrate residues pendant to the main chain (glycopolymers) were prepared by reversible addition fragmentation chain transfer (RAFT) polymerisation. Excellent control over molecular weight and narrow polydispersities (1.1–1.2) were achieved over a range of molecular weights. In addition, efficient synthesis of block copolymers by sequential monomer addition with both hydrophilic and hydrophobic non-carbohydrate blocks was demonstrated. The aqueous solution behaviour of amphiphilic block glycopolymers was investigated, revealing the formation of multivalent carbohydrate-bearing aggregates in solution with the capability for the solubilisation of hydrophobic species (a water-insoluble dye). One such amphiphilic glycopolymer shows by TEM the formation of a worm-like micelle phase. Further investigations of these novel bioactive macromolecular assemblies are underway.

Back to tab navigation

Publication details

The article was received on 07 Nov 2007, accepted on 07 Dec 2007 and first published on 09 Apr 2008


Article type: Paper
DOI: 10.1039/B717177C
Citation: Faraday Discuss., 2008,139, 359-368
  •   Request permissions

    Synthesis of well-defined glycopolymers and some studies of their aqueous solution behaviour

    N. R. Cameron, S. G. Spain, J. A. Kingham, S. Weck, L. Albertin, C. A. Barker, G. Battaglia, T. Smart and A. Blanazs, Faraday Discuss., 2008, 139, 359
    DOI: 10.1039/B717177C

Search articles by author

Spotlight

Advertisements