Functionalised cyclopentadienyl zirconium compounds as potential anticancer drugs

Olivia R. Allen; Richard J. Knox; Patrick C. McGowan

doi:10.1039/B812244J

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Dalton Transactions

Issue 39, 2008

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Functionalised cyclopentadienyl zirconium compounds as potential anticancer drugs

Olivia R. Allen , Richard J. Knox and Patrick C. McGowan

Dalton Trans., 2008, 5293-5295

DOI: 10.1039/B812244J
Received 17 Jul 2008, Accepted 07 Aug 2008
First published on the web 18 Aug 2008

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New neutral and ionic functionalised zirconocene dichloride compounds have been isolated and characterised. The ionic zirconocene exhibits excellent cytotoxicity against a range of human tumour cell lines, which represents the first active anticancer zirconocene dichloride compound.

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Dalton Transactions

Functionalised cyclopentadienyl zirconium compounds as potential anticancer drugs

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