Jump to main content
Jump to site search

Issue 12, 2008
Previous Article Next Article

Computational design of biological catalysts

Author affiliations


The purpose of this tutorial review is to illustrate the way to design new and powerful catalysts. The first possibility to get a biological catalyst for a given chemical process is to use existing enzymes that catalyze related reactions. The second possibility is the use of immune systems that recognize stable molecules resembling the transition structure of the target reaction. We finally show how computational techniques are able to provide an enormous quantity of information, providing clues to guide the development of new biological catalysts.

Graphical abstract: Computational design of biological catalysts

Back to tab navigation

Publication details

The article was received on 07 Jul 2008 and first published on 06 Oct 2008

Article type: Tutorial Review
DOI: 10.1039/B710705F
Citation: Chem. Soc. Rev., 2008,37, 2634-2643
  •   Request permissions

    Computational design of biological catalysts

    S. Martí, J. Andrés, V. Moliner, E. Silla, I. Tuñón and J. Bertrán, Chem. Soc. Rev., 2008, 37, 2634
    DOI: 10.1039/B710705F

Search articles by author