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Issue 7, 2008
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Chemical technologies for probing embryonic development

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Abstract

Embryogenesis is a remarkable program of cell proliferation, migration, and differentiation that transforms a single fertilized egg into a complex multicellular organism. Understanding this process at the molecular and systems levels will require an interdisciplinary approach, including the concepts and technologies of chemical biology. This tutorial review provides an overview of chemical tools that have been used in developmental biology research, focusing on methods that enable spatiotemporal control of gene function and the visualization of embryonic patterning. Limitations of current approaches and future challenges are also discussed.

Graphical abstract: Chemical technologies for probing embryonic development

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Publication details

The article was received on 03 Feb 2008 and first published on 07 May 2008


Article type: Tutorial Review
DOI: 10.1039/B703023C
Citation: Chem. Soc. Rev., 2008,37, 1294-1307
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    Chemical technologies for probing embryonic development

    I. A. Shestopalov and J. K. Chen, Chem. Soc. Rev., 2008, 37, 1294
    DOI: 10.1039/B703023C

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