Jump to main content
Jump to site search

Issue 2, 2008
Previous Article Next Article

Fluorine in medicinal chemistry

Author affiliations

Abstract

It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a sampling of renowned fluorinated drugs and their mode of action with a discussion clarifying the role and impact of fluorine substitution on drug potency.

Graphical abstract: Fluorine in medicinal chemistry

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 26 Nov 2007 and first published on 13 Dec 2007


Article type: Tutorial Review
DOI: 10.1039/B610213C
Citation: Chem. Soc. Rev., 2008,37, 320-330
  •   Request permissions

    Fluorine in medicinal chemistry

    S. Purser, P. R. Moore, S. Swallow and V. Gouverneur, Chem. Soc. Rev., 2008, 37, 320
    DOI: 10.1039/B610213C

Search articles by author