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Issue 44, 2008
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Trifluoromethyldiazirine: an effective photo-induced cross-linking probe for exploring amyloid formation

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Abstract

The separative and analytical power of ion mobility spectrometry-mass spectrometry combined with photo-induced cross-linking of site-specifically incorporated trifluoromethyldiazirine provides a powerful approach towards structural characterisation of amyloid fibrils.

Graphical abstract: Trifluoromethyldiazirine: an effective photo-induced cross-linking probe for exploring amyloid formation

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Publication details

The article was received on 04 Aug 2008, accepted on 05 Sep 2008 and first published on 30 Sep 2008


Article type: Communication
DOI: 10.1039/B813504E
Citation: Chem. Commun., 2008,0, 5728-5730
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    Trifluoromethyldiazirine: an effective photo-induced cross-linking probe for exploring amyloid formation

    D. P. Smith, J. Anderson, J. Plante, A. E. Ashcroft, S. E. Radford, A. J. Wilson and M. J. Parker, Chem. Commun., 2008, 0, 5728
    DOI: 10.1039/B813504E

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