Issue 46, 2008
From the journal:

Chemical Communications

Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(ii)macrocycle†

Ta-Sheng Andrew Tsenga  and  Judith N. Burstyn*a  

* Corresponding authors

a Department of Chemistry, University of Wisconsin, Madison, USA
E-mail: Burstyn@chem.wisc.edu
Fax: +1 608-262-6143
Tel: +1 608-262-0328

Abstract

An intercalator-linked macrocycle3,6-bis(dimethylamino)-10-(6-[1,4,7-triazacyclononane]hexyl) acridinium bromide was synthesized, its copper(II) complex was prepared, and the DNA cleavage activity of this metal complex was compared to that of the intercalator-free (Cu[9]aneN3)2+ complex.

Graphical abstract: Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(ii)macrocycle

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B812183D
Article type
Communication
Submitted
16 Jul 2008
Accepted
24 Sep 2008
First published
27 Oct 2008

Chem. Commun., 2008, 6209-6211

Permissions

Request permissions

Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(II)macrocycle

T. A. Tseng and J. N. Burstyn, Chem. Commun., 2008, 6209 DOI: 10.1039/B812183D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements