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Issue 40, 2008
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Efficient copper-free Sonogashira coupling of aryl chlorides with palladium on charcoal

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Abstract

Palladium on charcoal serves as an efficient and reusable solid supported catalyst for the Sonogashira coupling of aryl chlorides with terminal acetylenes in the presence of a bulky, electron-rich biphenyl type ligand (XPhos), without copper co-catalyst.

Graphical abstract: Efficient copper-free Sonogashira coupling of aryl chlorides with palladium on charcoal

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Publication details

The article was received on 27 Jun 2008, accepted on 11 Jul 2008 and first published on 08 Sep 2008


Article type: Communication
DOI: 10.1039/B810928A
Citation: Chem. Commun., 2008,0, 4968-4970
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    Efficient copper-free Sonogashira coupling of aryl chlorides with palladium on charcoal

    A. Komáromi and Z. Novák, Chem. Commun., 2008, 0, 4968
    DOI: 10.1039/B810928A

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