Issue 40, 2008

One-pot approach for the synthesis of trans-cyclopropyl compounds from aldehydes. Application to the synthesis of GPR40 receptor agonists

Abstract

A novel multicatalytic one-pot process providing trans-cyclopropyl compounds from corresponding aldehydes has been developed and applied to the synthesis of GPR40 small molecule agonists.

Graphical abstract: One-pot approach for the synthesis of trans-cyclopropyl compounds from aldehydes. Application to the synthesis of GPR40 receptor agonists

Supplementary files

Article information

Article type
Communication
Submitted
25 Jun 2008
Accepted
04 Aug 2008
First published
12 Sep 2008

Chem. Commun., 2008, 4974-4976

One-pot approach for the synthesis of trans-cyclopropyl compounds from aldehydes. Application to the synthesis of GPR40 receptor agonists

M. Davi and H. Lebel, Chem. Commun., 2008, 4974 DOI: 10.1039/B810708D

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