Synthesis and properties of DNA containing a spore photoproduct analog

Eva Bürckstümmer; Thomas Carell

doi:10.1039/B810008J

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Chemical Communications

Issue 34, 2008

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Synthesis and properties of DNA containing a spore photoproduct analog

Eva Bürckstümmer and Thomas Carell

Chem. Commun., 2008, 4037-4039

DOI: 10.1039/B810008J
Received 13 Jun 2008, Accepted 18 Jul 2008
First published on the web 30 Jul 2008

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Abstract
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The spore photoproduct is a unique photolesion, formed in spores upon irradiation with UV light; to investigate the properties of spore photoproduct containing DNA we have synthesized 5S and 5R lesion analogs and incorporated them into DNA.

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Supplementary Info

Synthesis of the SP-isomers 1a and 1b, HPLC chromatograms of the separated isomers 2a and 2b, ¹H-NMR spectra from 2a and 2b and NOE data for the isomers 2a/b, DNA melting curves
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Chemical Communications

Synthesis and properties of DNA containing a spore photoproduct analog

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