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Issue 26, 2008
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Ammonium salts as an inexpensive and convenient nitrogen source in the Cu-catalyzed amination of aryl halides at room temperature

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Abstract

Convenient and inexpensive ammonium salts such as NH4Cl and aqueous NH3 solution are found to be readily utilized in the Cu-catalyzed room temperature N-arylation of aryl halides, providing N-unprotected aniline derivatives in high yields.

Graphical abstract: Ammonium salts as an inexpensive and convenient nitrogen source in the Cu-catalyzed amination of aryl halides at room temperature

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Publication details

The article was received on 18 Mar 2008, accepted on 30 Mar 2008 and first published on 23 May 2008


Article type: Communication
DOI: 10.1039/B804637A
Citation: Chem. Commun., 2008,0, 3052-3054
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    Ammonium salts as an inexpensive and convenient nitrogen source in the Cu-catalyzed amination of aryl halides at room temperature

    J. Kim and S. Chang, Chem. Commun., 2008, 0, 3052
    DOI: 10.1039/B804637A

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