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Issue 14, 2008
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Facile acetal dynamic combinatorial library

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Abstract

We herein report our first results on the use of simple acetalation chemistry in the service of dynamic combinatorial libraries (DCLs); the reaction between triethylene glycol and 4-nitrobenzaldehyde afforded a DCL of more than 15 cyclic and acyclic species; all of which were separated and characterized; the smaller macrocyclic compounds were successfully amplified by the use of ammonium ions.

Graphical abstract: Facile acetal dynamic combinatorial library

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Publication details

The article was received on 10 Jan 2008, accepted on 25 Jan 2008 and first published on 07 Feb 2008


Article type: Communication
DOI: 10.1039/B800384J
Citation: Chem. Commun., 2008,0, 1686-1688
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    Facile acetal dynamic combinatorial library

    D. Berkovich-Berger and N. Gabriel Lemcoff, Chem. Commun., 2008, 0, 1686
    DOI: 10.1039/B800384J

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