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Issue 12, 2008
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Nucleotide insertion and bypass synthesis of pyrene- and BODIPY-modified oligonucleotides by DNA polymerases

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Abstract

The chromophores pyrene and bordipyrromethenylbenzene directly linked to the 5-position of uridine are tolerated and recognized as thymine derivatives by DNA polymerases in primer extension experiments.

Graphical abstract: Nucleotide insertion and bypass synthesis of pyrene- and BODIPY-modified oligonucleotides by DNA polymerases

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Publication details

The article was received on 20 Nov 2007, accepted on 07 Jan 2008 and first published on 29 Jan 2008


Article type: Communication
DOI: 10.1039/B718002K
Citation: Chem. Commun., 2008, 1443-1445
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    Nucleotide insertion and bypass synthesis of pyrene- and BODIPY-modified oligonucleotides by DNA polymerases

    C. Wanninger-Weiß, F. Di Pasquale, T. Ehrenschwender, A. Marx and H. Wagenknecht, Chem. Commun., 2008, 1443
    DOI: 10.1039/B718002K

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