Discovery of heparin chemosensors through diversity oriented fluorescence library approach

Shenliang Wang; Young-Tae Chang

doi:10.1039/B717058K

skip RSC | ChemSpider | Feedback

Home > Journals > Chemical Communications > Discovery of heparin ch...

Authors & Referees | Librarians

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Chemical Communications

Issue 10, 2008

More about this Journal
Editorial Board
Submit an Article

Follow Journal | |

Journal Home | RSC Journals

Communication

Previous Article | Next Article

Discovery of heparin chemosensors through diversity oriented fluorescence library approach

Shenliang Wang and Young-Tae Chang

Chem. Commun., 2008, 1173-1175

DOI: 10.1039/B717058K
Received 05 Nov 2007, Accepted 26 Nov 2007
First published on the web 11 Dec 2007

Please wait while Download options loads

Request Permissions

Abstract
Cited by
Compounds
Related Content

Two novel heparin sensors, Heparin Orange and Heparin Blue, were developed by a diversity oriented fluorescence library approach (DOFLA) from a benzimidazolium library; the discovered compounds showed remarkable properties and have the potential to be applied to monitoring heparin levels in clinical plasma samples for point-of-care detection.

This may take some time to load.

Supplementary Info

Complete experimental details; spectral data for Heparin Orange and Heparin Blue; fluorescence emission spectra of Heparin Orange and Heparin Blue upon addition of LMWH; fluorescent protamine titration of Heparin Orange and Heparin Blue; selectivity of Heparin Orange and Heparin Blue towards various biologically relevant analytes; picture of Heparin Orange and Heparin Blue with different concentrations of UFH and LMWH in pooled human plasma
PDF (9720K)

Terms & Conditions|Privacy |Accessibility|ACAP Enabled

Chemical Communications

Discovery of heparin chemosensors through diversity oriented fluorescence library approach

Log in (Free Access)

Log in (Subscriber Access)

Supplementary Info

Articles By