Chain-like assembly of gold nanoparticles on artificial DNA templates via ‘click chemistry’

Monika Fischler; Alla Sologubenko; Joachim Mayer; Guido Clever; Glenn Burley; Johannes Gierlich; Thomas Carell; Ulrich Simon

doi:10.1039/B715602B

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Chemical Communications

Issue 2, 2008

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Chain-like assembly of gold nanoparticles on artificial DNA templates via ‘click chemistry’

Monika Fischler , Alla Sologubenko , Joachim Mayer , Guido Clever , Glenn Burley , Johannes Gierlich , Thomas Carell and Ulrich Simon

Chem. Commun., 2008, 169-171

DOI: 10.1039/B715602B
Received 10 Oct 2007, Accepted 22 Nov 2007
First published on the web 29 Nov 2007

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Abstract
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We present a new type of azide-functionalized gold nanoparticle and their coupling to an alkyne-modified DNA duplex using the copper(I)-catalyzed Huisgen cycloaddition (‘click chemistry’), resulting in a chain-like assembly of nanoparticles on the DNA template.

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Supplementary Info

Further AFM and TEM analysis; experimental details
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Articles By

Monika Fischler
Alla Sologubenko
Joachim Mayer
Guido Clever
Glenn Burley
Johannes Gierlich
Thomas Carell
Ulrich Simon

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Chemical Communications

Chain-like assembly of gold nanoparticles on artificial DNA templates via ‘click chemistry’

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