A temperature independent pH (TIP) buffer for biomedical biophysical applications at low temperatures

Nathan A. Sieracki; Hee Jung Hwang; Michelle K. Lee; Dewain K. Garner; Yi Lu

doi:10.1039/B714446F

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Chemical Communications

Issue 7, 2008

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A temperature independent pH (TIP) buffer for biomedical biophysical applications at low temperatures

Nathan A. Sieracki , Hee Jung Hwang , Michelle K. Lee , Dewain K. Garner and Yi Lu

Chem. Commun., 2008, 823-825

DOI: 10.1039/B714446F
Received 19 Sep 2007, Accepted 03 Dec 2007
First published on the web 19 Dec 2007

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A temperature independent pH buffer has been developed from a combination of buffers of opposite-sign temperature coefficients, and utility in low temperature spectroscopy and storage of pH sensitive compounds is demonstrated.

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Experimental details including buffer preparation, low-temperature spectroscopy, and ESI-MS spectrum of oxacillin hydrolysis product
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Articles By

Nathan A. Sieracki
Hee Jung Hwang
Michelle K. Lee
Dewain K. Garner
Yi Lu

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Chemical Communications

A temperature independent pH (TIP) buffer for biomedical biophysical applications at low temperatures

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