Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry

Matthew J. Baker; Michael D. Brown; Ehsan Gazi; Noel W. Clarke; John C. Vickerman; Nicholas P. Lockyer

doi:10.1039/B712853C

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Analyst

Issue 2, 2008

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Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry

Matthew J. Baker , Michael D. Brown , Ehsan Gazi , Noel W. Clarke , John C. Vickerman and Nicholas P. Lockyer

Analyst, 2008, 133, 175-179

DOI: 10.1039/B712853C
Received 21 Aug 2007, Accepted 21 Nov 2007
First published on the web 30 Nov 2007

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This communication utilises Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) combined with multivariate analysis to obtain spectra from the surfaces of three closely related cell lines allowing their discrimination based upon mass spectral ions.

Abstract from Mass Spectrometry Bulletin 2008

Biochemical, Medical, Secondary ion mass spectrometry, Surface, Time-of-flight spectrometer.

Articles By

Matthew J. Baker
Michael D. Brown
Ehsan Gazi
Noel W. Clarke
John C. Vickerman
Nicholas P. Lockyer

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Analyst

Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry

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