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Issue 5, 2007
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Enzymatic control of the self-assembly of small molecules: a new way to generate supramolecular hydrogels

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Abstract

This highlight summarizes recent advances in the enzymatic formation of supramolecular hydrogels, a new method for the creation of biofunctional soft matter. Using phosphatase, thermolysin, β-lactamase, and phosphatase/kinase as examples, we illustrate the design and application of enzyme catalyzed or regulated formation of supramolecular hydrogels. This approach provides a new strategy to detect the presence of enzymes, screen enzyme inhibitors, assist biomineralization, assay the types of bacteria, and aid the development of smart drug delivery systems. The strategy of using enzymes to control the self-assembly of small molecules described in this highlight will lead to the further development of new materials for biomedical applications and improve understanding of molecular self-assembly in water.

Graphical abstract: Enzymatic control of the self-assembly of small molecules: a new way to generate supramolecular hydrogels

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Publication details

The article was first published on 15 Feb 2007


Article type: Highlight
DOI: 10.1039/B700138J
Citation: Soft Matter, 2007,3, 515-520
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    Enzymatic control of the self-assembly of small molecules: a new way to generate supramolecular hydrogels

    Z. Yang, G. Liang and B. Xu, Soft Matter, 2007, 3, 515
    DOI: 10.1039/B700138J

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