Issue 9, 2007

An efficient route for the synthesis of a new class of pyrido[2,3-d]pyrimidine derivatives

Abstract

A new reaction of 4-arylidene-3-methylisoxazol-5(4H)-one or 4-arylidene-2-phenyloxazol-5(4H)-one with 2,6-diaminopyrimidin-4(3H)-one is described and a number of new pyrido[2,3-d]pyrimidine-4,7-dione derivatives are synthesized. This protocol has the advantages of good yields, broad substrate scope and simple work-up.

Graphical abstract: An efficient route for the synthesis of a new class of pyrido[2,3-d]pyrimidine derivatives

Supplementary files

Article information

Article type
Paper
Submitted
30 Nov 2006
Accepted
13 Mar 2007
First published
28 Mar 2007

Org. Biomol. Chem., 2007,5, 1450-1453

An efficient route for the synthesis of a new class of pyrido[2,3-d]pyrimidine derivatives

S. Tu, J. Zhang, R. Jia, B. Jiang, Y. Zhang and H. Jiang, Org. Biomol. Chem., 2007, 5, 1450 DOI: 10.1039/B617201F

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