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Issue 7, 2007
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A microfluidic device based on droplet storage for screening solubility diagrams

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Abstract

This work describes a new microfluidic device developed for the rapid screening of solubility diagrams. In several parallel channels, hundreds of nanolitre volume droplets of a given solution are first stored with a gradual variation in the solute concentration. Then, the application of a temperature gradient along these channels enables us to read directly and quantitatively phase diagrams, concentration vs. temperature. We show, using a solution of adipic acid, that we can measure ten points of the solubility curve in less than 1 hr and with only 250 µL of solution.

Graphical abstract: A microfluidic device based on droplet storage for screening solubility diagrams

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Publication details

The article was received on 18 Jan 2007, accepted on 02 Apr 2007 and first published on 20 Apr 2007


Article type: Paper
DOI: 10.1039/B700799J
Citation: Lab Chip, 2007,7, 829-834
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    A microfluidic device based on droplet storage for screening solubility diagrams

    P. Laval, N. Lisai, J. Salmon and M. Joanicot, Lab Chip, 2007, 7, 829
    DOI: 10.1039/B700799J

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