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Issue 46, 2007
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Aminopropyltriethoxysilane (APTES)-functionalized nanoporous polymeric gratings: fabrication and application in biosensing

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Abstract

We have fabricated aminopropyltriethoxysilane (APTES)-functionalized nanoporous polymeric gratings by combining holographic interference patterning and APTES-functionalization of the pre-polymer syrup. The APTES facilitates the immobilization of biomolecules onto the polymeric grating surfaces. The successful detection of multiple biomolecules (biotin, steptavidin, biotinylated anti-rabbit IgG, and rabbit-IgG) indicates that the functionalized nanoporous polymeric gratings can act as biosensing platforms which are label-free, inexpensive, and applicable as high-throughput assays.

Graphical abstract: Aminopropyltriethoxysilane (APTES)-functionalized nanoporous polymeric gratings: fabrication and application in biosensing

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Publication details

The article was received on 23 Jul 2007, accepted on 28 Sep 2007 and first published on 12 Oct 2007


Article type: Paper
DOI: 10.1039/B711200A
Citation: J. Mater. Chem., 2007,17, 4896-4901
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    Aminopropyltriethoxysilane (APTES)-functionalized nanoporous polymeric gratings: fabrication and application in biosensing

    V. K. S. Hsiao, J. R. Waldeisen, Y. Zheng, P. F. Lloyd, T. J. Bunning and T. J. Huang, J. Mater. Chem., 2007, 17, 4896
    DOI: 10.1039/B711200A

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