The palladium complex of the new disulfonated 9-(3-phenylpropyl)-9′-PCy2-fluorene ligand is a highly active catalyst for aqueous Suzuki coupling reactions of N-heterocyclic chlorides and N-heterocyclic boronic acids; catalyst loadings of 0.02–0.1 mol% of Pd and two equiv. of phosphine result in the near quantitative formation of the respective coupling products at 100 °C.
Green Chemistry
- Information Point