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Issue 7, 2007
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Multi-component assessment of worker exposures in a copper refinery
Part 2. Biological exposure indices for copper, nickel and cobalt

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Abstract

Urinary copper (Cu), nickel (Ni) and cobalt (Co) concentrations were determined for 127 Cu refinery workers (40 females, 87 males), with values of the 95% upper confidence interval of the geometric mean in nmol per mmol creatinine of 89 (Ni), 42 (Cu) and 3.4 (Co) for electrorefinery workers. In the pyrometallurgical departments, the corresponding concentrations were 37 (Ni), 99 (Cu) and 11 (Co). Female workers had higher Co urinary concentrations than males (p ≤ 0.05) while no gender difference was observed for Cu and Ni. Inter-elemental correlations were moderate to weak. Based on the inhalable aerosol levels reported previously for the same workers, the observed urinary Cu concentrations were considerably lower than expected, relative to Co and Ni. This is interpreted in terms of the current understanding of Cu homeostasis.

Graphical abstract: Multi-component assessment of worker exposures in a copper refinery Part 2. Biological exposure indices for copper, nickel and cobalt

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Publication details

The article was received on 15 Dec 2006, accepted on 26 Apr 2007 and first published on 24 May 2007


Article type: Paper
DOI: 10.1039/B618400F
Citation: J. Environ. Monit., 2007,9, 695-700
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    Multi-component assessment of worker exposures in a copper refinery

    E. Nieboer, Y. Thomassen, N. Romanova, A. Nikonov, J. Øyvind Odland and V. Chaschin, J. Environ. Monit., 2007, 9, 695
    DOI: 10.1039/B618400F

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