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Issue 43, 2007
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Developing new metal-based therapeutics: challenges and opportunities

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Abstract

Unexpected side effects and problems experienced in clinical trials have created a difficult environment for those developing new pharmaceuticals and, as a consequence, the number of new chemical entities being registered has fallen to a historic low. Those developing metal-based therapeutics will face the same difficulties, but this environment also provides many opportunities for creative solutions to be applied to overcoming the problems and concerns. In this perspective, these challenges and opportunities are considered in the context of examples of a number of classes of metal-based therapeutics.

Graphical abstract: Developing new metal-based therapeutics: challenges and opportunities

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Publication details

The article was received on 23 Apr 2007, accepted on 16 May 2007 and first published on 04 Oct 2007


Article type: Perspective
DOI: 10.1039/B706075K
Citation: Dalton Trans., 2007,0, 4929-4937
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    Developing new metal-based therapeutics: challenges and opportunities

    T. W. Hambley, Dalton Trans., 2007, 0, 4929
    DOI: 10.1039/B706075K

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