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Issue 2, 2007
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Development of synthetic membrane transporters for anions

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Abstract

The development of low molecular weight anion transporters is an emerging topic in supramolecular chemistry. The major focus of this tutorial review is on synthetic chloride transport systems that operate in vesicle and cell membranes. The transporters alter transmembrane concentration gradients, and thus they have applications as reagents for cell biology research and as potential chemotherapeutic agents. The molecular designs include monomolecular channels, self-assembled channels and mobile carriers. Also discussed are the experimental assays that measure transport rates across model bilayer membranes.

Graphical abstract: Development of synthetic membrane transporters for anions

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Publication details

The article was received on 01 Sep 2006, accepted on 28 Sep 2006 and first published on 23 Oct 2006


Article type: Tutorial Review
DOI: 10.1039/B512651G
Citation: Chem. Soc. Rev., 2007,36, 348-357
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    Development of synthetic membrane transporters for anions

    A. P. Davis, D. N. Sheppard and B. D. Smith, Chem. Soc. Rev., 2007, 36, 348
    DOI: 10.1039/B512651G

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