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Issue 43, 2007
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Identification of protease substrates by combinatorial profiling on TentaGel beads

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Abstract

Reacting a 65 536 member combinatorial library of octapeptides on TentaGel beads with various proteases followed by selective staining of the free amino termini at the reacted bead surface and sequence determination by amino acid analysis allowed the rapid identification of protease substrates.

Graphical abstract: Identification of protease substrates by combinatorial profiling on TentaGel beads

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Publication details

The article was received on 05 Sep 2007, accepted on 05 Oct 2007 and first published on 11 Oct 2007


Article type: Communication
DOI: 10.1039/B713595E
Citation: Chem. Commun., 2007,0, 4453-4455
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    Identification of protease substrates by combinatorial profiling on TentaGel beads

    J. Kofoed and J. Reymond, Chem. Commun., 2007, 0, 4453
    DOI: 10.1039/B713595E

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