Using Congo red to report intracellular hydrogelation resulted from self-assembly of small molecules

Gaolin Liang; Keming Xu; Lihua Li; Ling Wang; Yi Kuang; Zhimou Yang; Bing Xu

doi:10.1039/B712971H

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Chemical Communications

Issue 40, 2007

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Using Congo red to report intracellular hydrogelation resulted from self-assembly of small molecules

Gaolin Liang , Keming Xu , Lihua Li , Ling Wang , Yi Kuang , Zhimou Yang and Bing Xu

Chem. Commun., 2007, 4096-4098

DOI: 10.1039/B712971H
Received 22 Aug 2007, Accepted 12 Sep 2007
First published on the web 19 Sep 2007

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Abstract
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This communication reports the use of Congo red to stain the nanofibers of self-assembled small molecules for assaying intracellular supramolecular hydrogels, which provides a convenient method to explore molecular self-assembly inside cells.

Supplementary Info

Synthesis, in vitro conversions of 2 to 3, 4 to 5, CD spectra of Gel I and Gel II, UV and fluorescence spectra of 1, MTT assay of 2 and 4
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Gaolin Liang
Keming Xu
Lihua Li
Ling Wang
Yi Kuang
Zhimou Yang
Bing Xu

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Chemical Communications

Using Congo red to report intracellular hydrogelation resulted from self-assembly of small molecules

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