Colorimetric Cu2+ detection with a ligation DNAzyme and nanoparticles

Juewen Liu; Yi Lu

doi:10.1039/B712421J

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Colorimetric Cu²⁺ detection with a ligation DNAzyme and nanoparticles†

Juewen Liu^a and Yi Lu*^a

Author affiliations

* Corresponding authors

^a Department of Chemistry, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA
E-mail: yi-lu@uiuc.edu
Fax: +1-217-333-2685
Tel: +1-217-333-2619

Abstract

Using a Cu²⁺-dependent DNA ligation DNAzyme, a colorimetric sensor for Cu²⁺ has been developed based on directed assembly of DNA-functionalized gold nanoparticles by the ligation product, and such ligation DNAzyme-based sensors are intrinsically more sensitive than cleavage DNAzyme systems due to the lack of background.

Download options Please wait...

Supplementary files

Experimental procedures for preparing nanoparticles, ligation reactions and Cu ²⁺ detection PDF (228K)

Article information

DOI: https://doi.org/10.1039/B712421J
Article type: Communication
Submitted: 13 Aug 2007
Accepted: 04 Oct 2007
First published: 24 Oct 2007

Download Citation

Chem. Commun., 2007, 4872-4874

Permissions

Request permissions

Colorimetric Cu²⁺ detection with a ligation DNAzyme and nanoparticles

J. Liu and Y. Lu, Chem. Commun., 2007, 4872 DOI: 10.1039/B712421J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications