Non-covalent interactions of a drug molecule encapsulated in a hybrid silica gel

Geo Paul; Stefan Steuernagel; Hubert Koller

doi:10.1039/B711105C

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Chemical Communications

Issue 48, 2007

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Non-covalent interactions of a drug molecule encapsulated in a hybrid silica gel

Geo Paul , Stefan Steuernagel and Hubert Koller

Chem. Commun., 2007, 5194-5196

DOI: 10.1039/B711105C
Received 19 Jul 2007, Accepted 11 Oct 2007
First published on the web 17 Oct 2007

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The drug molecule Propranolol has been encapsulated by a sol–gel process in an organic–inorganic hybrid matrix by in-situ self-assembly; the 2D HETCOR solid state NMR spectroscopy provides direct proof of the intimate spatial relationship between the host matrix and guest drug molecules.

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Chemical Communications

Non-covalent interactions of a drug molecule encapsulated in a hybrid silica gel

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