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Issue 41, 2007
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CO and NO in medicine

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The occurrence, role and consequences of CO and NO in biological systems are reviewed. This includes their syntheses by heme oxygenases and NO synthases, their biological targets and the physiological effects of their signals. The use of CO and NO gases in medicine are discussed and methods of delivery are illustrated with particular emphasis on the therapeutic properties of compounds that generate controlled amounts of NO and COin vivo.

Graphical abstract: CO and NO in medicine

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Publication details

The article was received on 30 Mar 2007, accepted on 15 May 2007 and first published on 14 Jun 2007

Article type: Feature Article
DOI: 10.1039/B704873D
Citation: Chem. Commun., 2007, 4197-4208
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    CO and NO in medicine

    B. E. Mann and R. Motterlini, Chem. Commun., 2007, 4197
    DOI: 10.1039/B704873D

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