Ligand-based backbone modifications for metal-chelating nucleic acids

Megan M. Knagge; Jonathan J. Wilker

doi:10.1039/B704741J

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Chemical Communications

Issue 32, 2007

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Ligand-based backbone modifications for metal-chelating nucleic acids

Megan M. Knagge and Jonathan J. Wilker

Chem. Commun., 2007, 3356-3358

DOI: 10.1039/B704741J
Received 29 Mar 2007, Accepted 18 May 2007
First published on the web 13 Jun 2007

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Abstract
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Ligands were incorporated into the backbone of DNA for nucleoside replacements, and the binding of metal ions, such as Cu²⁺, Pt²⁺ and Pd⁴⁺, was shown to influence stability of the resulting duplexes.

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Chemical Communications

Ligand-based backbone modifications for metal-chelating nucleic acids

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