Site-selective depurination by a periodate-dependent deoxyribozyme

Claudia Höbartner; P. I. Pradeepkumar; Scott K. Silverman

doi:10.1039/B704507G

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Chemical Communications

Issue 22, 2007

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Site-selective depurination by a periodate-dependent deoxyribozyme

Claudia Höbartner , P. I. Pradeepkumar and Scott K. Silverman

Chem. Commun., 2007, 2255-2257

DOI: 10.1039/B704507G
Received 26 Mar 2007, Accepted 03 May 2007
First published on the web 10 May 2007

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Abstract
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A deoxyribozyme is identified that mediates the site-selective depurination of its 5′-terminal guanosine nucleotide using periodate (IO₄⁻) as an obligatory cofactor.

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Chemical Communications

Site-selective depurination by a periodate-dependent deoxyribozyme

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