Issue 26, 2007
From the journal:

Chemical Communications

Reagentless electrochemical immunoassay using electrocatalytic nanoparticle-modified antibodies†

Ronen Polsky,a   Jason C. Harper,a   David R. Wheeler,a   Shawn M. Dirk,a   Julia A. Rawlingsa  and  Susan M. Brozik*a  

* Corresponding authors

a Sandia National Laboratories, PO Box 5800, MS-0892, Albuquerque, NM, USA
E-mail: smbrozi@sandia.gov
Fax: +1 (505)845-8161
Tel: +1 (505)844-5105

Abstract

We describe a new approach for reagentless electrochemical immunoassay sensing in which Au/Pd NPs can be “loaded” onto antibodies to create an electrocatalytic antibody that is sensitive to the oxygen reduction reaction.

Graphical abstract: Reagentless electrochemical immunoassay using electrocatalytic nanoparticle-modified antibodies

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Article information

DOI
https://doi.org/10.1039/B704012A
Article type
Communication
Submitted
16 Mar 2007
Accepted
18 Apr 2007
First published
04 May 2007

Chem. Commun., 2007, 2741-2743

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Reagentless electrochemical immunoassay using electrocatalytic nanoparticle-modified antibodies

R. Polsky, J. C. Harper, D. R. Wheeler, S. M. Dirk, J. A. Rawlings and S. M. Brozik, Chem. Commun., 2007, 2741 DOI: 10.1039/B704012A

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